GN4 system is shipped with a ready-to-use typography named Default.
DO NOT DELETE or rename the Default typography.
If your system has only one publication, add a new typography and import your fonts and create styles for text formatting.
If your system has more publications with different formatting, add more typographies for other publications.
This step has to be accomplished before any other.
Moreover, a typography has a set of values you need to create manually, such as colors, stroke styles, copy-fit sets, word estimate, start/end shapes, fonts, hyphenations, formats and styles.
See also
Configuring Typographies (chapter)