Protected mode can prevent ClickOnce to install and run successfully on your computer.

Internet Explorer 8 or 9 protected mode is a feature that makes it more difficult for malicious software to be installed on your computer.

In addition to helping protect your computer from malicious software, protected mode allows you to install wanted ActiveX controls or add-ons when you are logged in as an administrator.

Protected mode is turned on by default in the Internet, Local intranet, and Restricted sites zones and an icon appears on the status bar (see example screenshot below) to let you know that it's running. This will show you how to turn protected mode on or off in each of these security zones.

Adding the GN4 URL to Trusted sites

If you want to keep protected mode on for Internet (recommended), you can add the GN4 URL to trusted sites (Internet options > Security > Trusted sites > Sites.

Protected mode and UAC

If you turn off UAC, then this will also disable protected mode for all users on the computer no matter if you have protected mode turned on or off in Internet Explorer below.

You must have UAC set to the default level below or higher to be able to turn on Protected Mode in Internet Explorer.